How do you treat grain poisoning in cattle?

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Consult a veterinarian for a treatment plan, as treatment will vary according to the severity of the disease. Treatments include intravenous fluids, drenching with bicarbonate solution or milk of magnesia, intraruminal antibiotic injections, thiamine or steroid injections, and surgery for very valuable animals.
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Antibiotics. If your doctor suspects that salmonella bacteria have entered your bloodstream, or if you have a severe case or a compromised immune system, he or she may prescribe antibiotics to kill the bacteria. Antibiotics are not of benefit in uncomplicated cases.
Use a chlorine bleach solution with a concentration of 1000–5000 ppm (5–25 tablespoons of household bleach [5.25%] per gallon of water) or other disinfectant registered as effective against norovirus by the Environmental Protection Agency (EPA)..
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You may shower or bathe with the blister (filled with fluid) or even if it is "broken open". Using soap and warm water, you may wash the area with clean fingers. Do not use a scented or antibacterial soap. Avoid going into a pool, river, lake, spa, hot tub, or sauna until the blister is dried up..