How painful is the stinging nettle?

Online Answer
Stinging nettle has fine hairs on the leaves and stems that contain irritating chemicals, which are released when the plant comes in contact with the skin. The hairs, or spines, of the stinging nettle are normally very painful to the touch.
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Nettles produce new shoots from their roots so it is important to use a systemic herbicide such as glyphosate that will move into the root system and kill the entire plant. Applications using a hand-held or backpack sprayer with a 2% glyphosate concentration are effective in nettle control.
Stinging nettle has fine hairs on the leaves and stems that contain irritating chemicals, which are released when the plant comes in contact with the skin. The hairs, or spines, of the stinging nettle are normally very painful to the touch.
The nettle family is full of stinging plants, but none is quite as aggressive as the gympie gympie (Dendrocnide moroides). ... The stinging leaves trigger an intense allergic reaction in its victims, sometimes even causing anaphylactic shock.