What is a BBQ smoker?

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Answer: A smoker is an apparatus for cooking at low temperatures in a controlled, smoky environment for the smoking of food. It's a piece of cooking equipment for making barbecue. ... Smokers are powered by a wide variety of fuels, including electricity, propane or natural gas, wood, charcoal, and pellets.
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PAHs are carcinogenic substances formed when fat and juices from meats drip onto a fire, causing flames that coat the food above with PAHs. PAHs can also be formed in smoke from charcoal or wood pellets, scientists say. ... Scientists say there is no good evidence pellet grilling is healthier than other grilling methods.
Once assembled, it's time for a burn-in. In many circles, "the burn-in" is referred to as seasoning. The main purpose of a burn-in is to remove any contaminants left over from the manufacturing process. At its core, the burn-in is simply running the smoker at an elevated temperature for two to three hours without food.
Green tea can reduce the risk of lung cancer in smokers. Benefits were also seen in non-smokers. Drinking green tea could modulate the effect of smoking on lung cancer.
The study shows that smokers die relatively young. An estimated 23 percent of consistent heavy smokers never reach the age of 65. This is 11 percent among light smokers and 7 percent among non-smokers. Life expectancy decreases by 13 years on average for heavy smokers compared to people who have never smoked.
So to answer your question. Yes you can over cook a pork shoulder or butt, brisket, roast etc. It is possible to run the gamut and over cook or over smoke food leaving a perfectly good piece of meat totally dried out or burned.