Is the Black Death still around?
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An outbreak of the bubonic plague in China has led to worry that the "Black Death" could make a significant return. But experts say the disease isn't nearly as deadly as it was, thanks to antibiotics.
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It was believed to start in China in 1334, spreading along trade routes and reaching Europe via Sicilian ports in the late 1340s. The plague killed an estimated 25 million people, almost a third of the continent's population. The Black Death lingered on for centuries, particularly in cities.
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Summary: Yersinia pestis, the deadly bacterium that causes bubonic plague, kills by cutting off a cell's ability to communicate with other immune system cells needed to fight off the bacterial invasion.Sep 17, 1999.
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Plague notices At times of plague, it was common to mark the doors of victims of the disease with a large painted cross, either in red or black paint. In later times, large printed crosses were often affixed to doors..
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The idea to develop vaccine against plague started by Alexandre Yersin in 1895 who investigated immunity against Y. pestis in small animal models in his laboratory. He evaluated heat-killed whole-cell vaccine, attenuated live strains of Y. pestis, by immunization in animals with repeated boosters (17).
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Shocking vision emerged from the mouse plague in New South Wales this year and, while the threat has plateaued in some areas, numbers are reportedly on the rise in parts of Victoria, southern NSW, southern Queensland and into South Australia.
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