What happens if you braise too long?

Online Answer
However, braised dishes like pot roast can be overcooked in spite of the moist heat cooking method. Pot roast that is cooked too long will fall apart and begin to lose moisture and tenderness..
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You want something with plenty of connective tissue and fat. The idea is that over the long cooking time, all that tissue softens and becomes gelatinous, giving well-braised meat a juicy, tender flavor. You wouldn't use a filet mignon or a rib-eye for braising because the end result would be very tough and overcooked.